You can change the destination in [Online] -> [Specify Connection Destination]. Change the destination depending on the communication path to be used. You can check the set connection path in an illustration by clicking [System Image].
Mitsubishi PLCs have three main options for modular PLC systems, being the Melsec-Q, Melsec-L, and the Melsec-iQ-R (recommended) The following Modular PLC system online selection tools are available: Melsec iQ-R Melsec-Q ...
Mitsubishi PLCs have two main options for compact PLC systems, being the FX3 and the FX5 (recommended) (aka iQ-F). The following Compact PLC system online selection tools are available: Melsec-FX Melsec iQ-F